Endocrine Abstracts

Introduction: Nephrolithiasis and bone disease are the most common complications of primary hyperparathyroidism (PHPT). The aim of this study was to evaluate the relationships between the existence of kidney stones, renal function and bone mineral density (BMD) in PHPT.Description of methods/design: Biomedical evaluation, BMD measurements and renal ultrasonography were performed in a group of 75 consecutive PHPT patients aged 57.6±12.7 years. The co...

The adrenal incidentalomas have become a common clinical problem. In the vast majority of cases these masses are non- secreting adrenocrotical adenomas. However, some may show minor endocrine abnormalities with a subclinical hyperfunction or represent malignancies.Objectives: The aim of the study was to analyze and follow-up of incidentalomas and to establish the risk factors for mass enlargement and/or hormonal disturbances.Materi...

Introduction: Primary hyperparathyroidism (PHPT) is generally associated with increased fracture risk at all skeletal sites although greater bone loss is observed at the cortical than the trabecular bone sites. AsBMD alone does not adequately predict fracture risk, trabecular bone score (TBS) is proposed as a new method supporting risk assessment.The aim of this study was to investigate correlation between TBS andthe severity of primary hyperparathyroidi...

Background: Calcium and vitamin D malabsorption in celiac disease (CD) predispose to high bone turnover and skeletal demineralization. Osteoprotegerin (OPG), a member of the tumor necrosis factor receptor family, and ligand of receptor activator of NFkB (RANKL) inhibits osteoclast formation and activity.The aim of this study was to evaluate the relationship between bone mineral density (BMD), bone-turnover markers and osteprotegerin in adult patients wit...

Background/Aims: Calcium and vitamin D malabsorption in celiac disease predispose to skeletal demineralization. The aim of this study was to evaluate the prevalence of bone mineral density (BMD) and calcium deficiencies in adult patients with CD and assess whether a gluten-free diet is sufficiently effective for BMD restoration or whether calcium and vitamin D should be applied.Methods: BMD and biochemical parameters of bone and mineral metabolism were m...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder. Beside renal and skeletal complications, it has a wide variety of nonspecific symptoms from other organs that may mimic other diseases and delay the diagnosis. Nowadays PHPT evolves to less-symptomatic.Aim: The aim is to revise symptomatology profile of PHPT in a single region of Poland; and to help early PHPT diagnosis – encouraging interdisciplinary contact between me...